The paper presents an analysis of the operation of 24 light commercial vehicles that constitute the transportation fleets of seven companies carrying out transport orders over a period of two years. The purpose of the study was to evaluate the effectiveness of operation of various light commercial vehicles with a focus on three groups formed according to their initial mileage, year of manufacture, or vehicle model. An evaluation of the effectiveness of each transport company is also presented. Based on an analysis of daily observations, technical and operational parameters were determined to be used as the basis for the development of a set of operational indicators that would enable evaluation of the effectiveness and safety of the performance of transport tasks. The proposed method for examining the effectiveness of operation of light commercial vehicles showed significant differences in the vehicle operation management strategies of various transportation companies. The developed set of operational indicators can be used as a tool to support decision-making in terms of safety in the performance of transport tasks and the effectiveness of the vehicle operation process.